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Cake day: June 23rd, 2023

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  • Not to mention meeting standards of purity and formulating your medication so it’s shelf stable and the active pharm ingredient can be distributed within the body effectively once the medicine is administered.

    I’ve had similar thoughts as these jokers but with using bioreactors. Each time I conclude that the solution is a centralized manufacturing facility owned by workers to effectively produce at scale (and ensure you don’t poison people).

    Sure, you’re not gonna build that misoprostol plant in Texas, but there’s other options to obtain properly-manufactured medication before you drink a mystery brew cooked up by an anarchist squatter named Spoon.


  • Absolutely, and I don’t see biohackers offering up cheap NMR or MS/MS detectors to solve the common issue of inadvertently making side products like MPTP when attempting to cook up MPPP or whatever, consequently injecting Parkinson’s into yourself. So you’re still bound by the enormous costs of getting an analytical lab stood up, despite using “AI” assisted synthetic software to substitute for real verification of each purified intermediate product. Also my other chem friend & I think that Vinni guy is an annoying ted-talk dude fwiw.


  • Very cool that they’ve published a FOSS version of in-silico synthetic software plus designed a jacketed reactor (much more convenient than babysitting a round bottomed flask in a mantle for 12 hours), but I can’t see it getting to very high or even mildy low temps.

    I don’t see much about cleaning the reactor feedlines or reactant reservoirs, nor how you take a reaction product and work it up, or purify it for that matter, in preparation for the next synthetic step. Classico synthesis traditionally structurally elucidates each step’s purified product with NMR before carrying it forward to the next rxn. But I’m a lazy chemist so I’d prefer to program microbes to make things for me (: