Water is “almost identical” to hydrogen peroxide.
Food and poop are both composed of atoms, so there’s essentially no difference between them.
Here’s an article by a psychiatrist that goes into more detail.
This study asks abusers how much they use in an average day, and gets numbers from about 300 to 800 mg. An average clinical dose of either Adderall or Desoxyn would be about 20 mg a day.
It also talks about that meth acting more quickly (which can make it more addicting), and people injecting or snorting it (which makes it act more quickly).
Nice source/quote! Just to add my personal experience, when I was first put on modafinil (diphenylmethyl-sulfinylacetamide) for debilitating fatigue and brain fog, I asked my doctor if I’d experience a high or feel super focused. He explained that taking 200mg of modafinil would make an otherwise healthy person 20% more stimulated (for example). But there’s something wrong with me so I’m only functioning at 60% to begin with. When I take 200mg modafinil it also stimulates me by 20%, but that only brings me up to 90% of what a normal healthy person feels like anyway. So I don’t feel a high, I just feel closer to normal. That’s heavily paraphrased and really oversimplified, but it helped me understand it a bit better when I was young and worried about taking all these medications.
I came here to talk about methyl groups and no one gives them a mention :(
I’m not a chemist but I like drugs. What’s up with methyl groups?
A methyl group is the name given to single carbon (with 3 hydrogens attached) when substituted onto a larger chemical moiety (a structure or motif in chemistry). When people speak about methyl groups they’re mostly speaking about those single carbon methyl group being attached to a heteroatom (atoms other than carbon and hydrogen in organic chemistry, like nitrogen, oxygen, sulfur, etc.).
Methamphetamine (N-methylamphetamine or N-methyl alpha-methyl-phenyl-ethylamine in full form) has a methyl group on it’s amine (nitrogen or N-position), which drastically alters its psychological effects and the way it’s synthesized by chemists (requiring methylamine). The methyl group there prolonges the stimulating effects, while also providing serotonergic effects (generally euphoric effects caused by interaction with the serotonin receptor transport protein), which gives it much greater addiction potential.
Methyl groups in general don’t “make drugs stronger” like the other guy said. To consider drug receptor interaction you need to take into account how well a molecule fits into the receptor you’re targetting as a whole.
Thats super interesring. It always amazes me how a small modification like a methyl group can so drastically alter the psychoactive properties of a substance. The body is such a nuanced and complicated system, its fascinating.
I really hope drug laws change so that we can see more research being done. Things like this help us learn more about not just the sustance, but the way our chemisty works & how our concious experience is shaped.
If you have any cool links on this topic, id love to browse them. Either way thanks for your run down on methyl groups :)
Garbage post, “redditor here!1!!” levels of cringe.
Are we seriously going to repost from facebook now?
Just like on the original Reddit sub, reposts from any and all social media are permitted. It’s basically the point of this community. All posts on here to date have been reposted from Reddit, and about a third of those originated on Facebook. But a big thank you @DominicHillsun for the first homegrown OC - I’m the creator and mod of this community, as well as OP.
How very apropos of you, OP. It’s DYKWIA inception. 🧑🍳🤌🏼🤣
I wondered if I was a bit close to breaking my own “don’t be dick” rule, but I couldn’t resist!
deleted by creator
Do you think I came down on the wrong side of being a dick? I haven’t modded before, it’s just me, and it’s really hard to decide where to draw the line. I don’t want to be a hypocrite and I don’t want to be too heavy handed in removing comments or banning people if it comes to that.
My thought process here was this guy’s initial comment was dickish but not to the point where it required removing their comment. I felt it was unnecessarily rude, but I don’t have the thickest skin. My reply was completely accurate and not rude, but it was heavy on the sarcasm. My ruling: neither of us broke the rule. What’s your take on it?
I stickied a post to the top of this community inviting feedback and suggestions on how to mod this community and what the rules should be. I’m also looking for more people to mod this community with me. I’m actively encouraging input and feedback so please add your thoughts to the stickied post - I genuinely want more people than just me deciding what’s ok and what’s not.
The reply is dumb but the re-reply is cringe lol
Agreed. If the credentials in their second comment were what qualified the statement in the first comment, why did they sign the first comment “licensed psychologist”, a title that doesn’t inherently qualify someone to speak to the pharmacological question.
And this being the internet, of course they’re qualified, why else would they rattle off a bunch of topics they’ve supposedly mastered? Surely no one on the internet would ever lie to win an argument!
People wonder why everyone on the internet is so full of shit, but then they take something like this at face value.
And the thing is, it’s actually somehow less cringe if they’re making the whole thing up. Healthy, well adjusted adults don’t argue with strangers on facebook, and they definitely don’t list random topics they’ve studied to “win” the argument. On reddit there used to be an allegory about pigeons and chess that applies here.
But my money is still on this person having no psychology degree whatsoever, because…I’m not new to the freakin’ internet. Cheap, unprovable claims to authority should be dismissed as easily as they’re written.
If you’re saying something factually verifiable or properly sourced then fine, but rattling off “credentials” to internet strangers is cringe af and always will be. I take it as an immediate sign that you’re not confident in your facts and are hoping to avoid or deflect scrutiny.
Agreed. Comments should only be valued as much as their inherent value in the eyes of the reader, or through the reputable sources they cite. Claimed external qualifications are pointless.
I mean, Methamphetamine is extremely similar, pharmacologically, with Adderall. Desoxyn is the ‘medicine brand name’ for meth, to treat ADHD.
Biggest difference between Crystal Meth, the street drug, and Desoxyn, the medicine, is dosage. A Desoxyn tablet is about 100x less methamphetamine than you’d take to ‘get high’. (not to mention, pills have a slower release than smoking it).
And yeah, there are other differences between Adderall and Meth; for the most part, Adderall is safer, less addictive, and less ‘makes you high’. So there’s very few people still using Desoxyn, but it is still out there. For reasons that aren’t really understood, Methamphetamine does work to treat a few people’s ADHD for whom Adderall doesn’t do much.
(and, for that matter, there are a pretty huge array of different amphetamines to treat ADHD and similar things, that are all subtly different in not very well understood ways, made messier by the fact that pharmaceutical companies making sure to push out a new drug, that might just be a new mix of existing drugs, every 10 years, for patent reasons. But Desoxyn is basically a ‘last resort’ to throw at the wall, if the patient hasn’t responded well to any of the others.)
I’m just putting this out there, that, cocaine also helps treat ADHD.
It’s not used in clinical treatments, but it has been observed that while neurotypical brains exposed to cocaine get an unfocused energy increase, ADHD brains tend to get a higher level of focus with that energy increase.
Theoretically it’s possible for someone to treat their own ADHD using cocaine.
… It’s a really bad idea, but it’s possible.
I mean, original coca cola, or even chewing coca leaves like South Americans could probably do the trick.
I feel like the biggest difference by far is that most amphetamines are prescribed in XR formulations these days. The feeling caused by a slow trickle of product from a laser-drilled capsule or time-release beads over 8-12 hours is incomparable to the rush of smoking or snorting powdered amphetamine. For a lot of drugs the biggest addiction driver is actually the rise rate which causes the “hit”. i.e. compare addictive cigarettes with nearly harmless pipe.
That’s why when people abuse Adderall they usually crush it up and toot it, and they aren’t railing 100 tablets at a go.
Myself I have taken Adderall and now take Dexadrine (it’s cheaper) and have never felt any addictive pull from either. When I go camping I always take a multi-day break and never feel any ill effects other than a desire to chase squirrels and bother strangers with excessive chat.
I always bring some with me though so I can take one on the last day and effectively pack up my campsite without leaving anything behind, lol
